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Mickaël Canouil
Curriculum Vitæ
I am currently working as a consultant in Biostatistics in the field of genetics, i.e., proteomics, metabolomics, transcriptomics, etc. in Lille & Paris, France.
Education
Oct. 2014Sep. 2017
Doctor of Philosophy (Ph.D.) in Biostatistics
University of Lille Lille, FranceSep. 2009Jul. 2011
Master’s Degree in Biostatistics, Bioinformatics and Genomics (Specialised in Biostatistics)
University Claude Bernard Lyon 1 Lyon, FranceSep. 2006Jul. 2009
Bachelor’s Degree in Biology (Specialised in Biostatistics)
University Claude Bernard Lyon 1 Lyon, FranceProfessional Experience
Nov. 2022Present
Consulting Senior Biostatistician (IT&M Stats)
L’Oréal Lille, FranceActivities: Statistical analyses of lipidomics and microbiome data
Jan. 2020Oct. 2022
Head of Biostatistics (Institut Pasteur de Lille)
Functional (Epi)genomics and MolecularPhysiology of Diabetes and Related Diseases
Inserm U1283 / CNRS UMR 8199 - EGID
(European Genomics Institute for Diabetes) Lille, France
Activities: Genome-wide association studies, experimental design, -omics data analysis, methodological developments, team management
Oct. 2017Dec. 2019
Head of Biostatistics (Institut Pasteur de Lille)
Laboratory of Integrated Genomicsand Metabolic Diseases Modeling
CNRS UMR 8199 - EGID
(European Genomics Institute for Diabetes) Lille, France
Activities: Genome-wide association studies, experimental design, -omics data analysis, methodological developments, team management
Jan. 2016Sep. 2017
Head of Biostatistics (CNRS)
Laboratory of Integrated Genomicsand Metabolic Diseases Modeling
CNRS UMR 8199 - EGID
(European Genomics Institute for Diabetes) Lille, France
Activities: Genome-wide association studies, experimental design, -omics data analysis, methodological developments, team management
Sep. 2012Dec. 2015
Biostatistician (CNRS)
Laboratory of Integrated Genomicsand Metabolic Diseases Modeling
CNRS UMR 8199 - EGID
(European Genomics Institute for Diabetes) Lille, France
Activities: Genome-wide association studies, experimental design, -omics data analysis, methodological developments
Nov. 2011Dec. 2011
Biostatistician
French Institute of Science and Technology forTransport, Development and Networks
(IFSTTAR)
UMRESTTE - UMR T9405 Bron, France
Activities: Analysis of a mobility and accident study in secondary-school pupils
Jan. 2011Jun. 2011
Biostatistician (Internship)
Hospices Civiles de LyonBiostatistics Unit
CNRS UMR 5558 Lyon, France
Activities: Development of a Non-Parametric (on Time) Clustering Algorithm for Longitudinal Data
Mar. 2010Jun. 2010
Biostatistician (Internship)
Biometry and Evolutionary Biology laboratory(LBBE)
CNRS UMR 5558 Lyon, France
Activities: Mathematical Modelling of Nosocomial Rotavirus Infections in Pediatric Ward
Workshop Experience (7)
Awards (1)
Mar. 2015
Funding Allocation SFD-Lilly
“Société Francophone du Diabète”(SFD) Bordeaux, France
Project: Detection of new genomic variants associated with fasting blood glucose and incidence of type 2 diabetes simultaneously
Oral communications (6)
Apr. 2021
My Journey To Transparency And Reproducibility
R Lille (rlille.fr) Online (Lille, France)Apr. 2021
My Journey To Transparency And Reproducibility (French)
Min2Rien (wwwJan. 2021
“Débuter” avec R en Commençant par le Début … (French)
R Lille (rlille.fr) Lille, FranceJan. 2019
Jointly Modelling SNPs With Survival & Longitudinal Trait
A Statistical Seminar Applied on Type 2 Diabetes(Host: Pr. Paul Franks) Lund, Sweden
Oct. 2018
Jointly Modelling SNPs With Survival & Longitudinal Trait
Thematic Day “Statistic & Genomic”of the “Réseau Interdisciplinaire
autour de la Statistique”
(RIS) (ris.cnrs.fr) Paris, France
Feb. 2016
Longitudinal Genetic Modelling: Revisiting Associations of SNPs Associated With Blood Fasting Glucose in Normoglycemic Individuals
Statistical Methods for Post Genomic Data(SMPGD) (math.univ-lille1.fr/~celisse/SMPGD) Lille, France
Poster communications (4)
Mar. 2017
“Variants Génétiques Associés à la Trajectoire de la Glycémie à Jeun et à l’Incidence du Diabète de Type 2: Une Approche par Modèle Joint” (CA-075)
Annual Congress of“Société Francophone du Diabète”
(SFD) Lille, France
Nov. 2016
Single Nucleotide Polymorphisms Associated With Fasting Blood Glucose Trajectory And Type 2 Diabetes Incidence: A Joint Modelling Approach
4th SymposiumEuropean Genomic Institute for Diabetes
(EGID) Lille, France
Oct. 2016
Single Nucleotide Polymorphisms Associated With Fasting Blood Glucose Trajectory And Type 2 Diabetes Incidence: A Joint Modelling Approach
International Genetic Epidemiology Society(IGES) Toronto, Canada
Oct. 2015
Application of Joint Models in Genetic Association Studies
International Genetic Epidemiology Society(IGES) Baltimore, United-States
R Packages (6)
Nov. 2020
insane: An Interactive Web Application for Quality Control and Analysis of Insulin Secretion from Pancreatic Beta Cells
(As author / creator) CRAN
May 2020
ggpacman: A ‘ggplot2’ and ‘gganimate’ Version of Pac-Man
(As author / creator) CRAN
Feb. 2020
ggnetwork: Geometries to Plot Networks with ‘ggplot2’
(As contributor) CRAN
Jun. 2018
NACHO: NanoString Quality Control Dashboard
(As author / creator) CRAN
Feb. 2014
clere: Simultaneous Variables Clustering and Regression
(As author) CRAN
Apr. 2013
snpEnrichment: SNPs Enrichment Analysis
(As author / creator) CRAN
Publications (7 + 36)
Sep. 2021
Epigenome-Wide Association Study Reveals Methylation Loci Associated With Offspring Gestational Diabetes Mellitus Exposure and Maternal Methylome
Mickaël Canouil†, Amna Khamis, Elina Keikkala, Sandra Hummel, Stephane Lobbens, […], Marjo-Riitta Jarvelin, Sylvain Sebert, Eero Kajantie, Philippe Froguel and Toby Andrew
Diabetes Care
† As first or co-first author.
Feb. 2020
: an R package for quality control of NanoString nCounter data
Mickaël Canouil†, Gerard A Bouland, Amélie Bonnefond, Philippe Froguel, Leen M ’t Hart and Roderick C Slieker
Bioinformatics
† As first or co-first author.
Jun. 2019
Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetes
Amna Khamis, Mickaël Canouil†, Afshan Siddiq, Hutokshi Crouch, Mario Falchi, […], Mark Ibberson, Amelie Bonnefond, Piero Marchetti, Michele Solimena and Philippe Froguel
Molecular Metabolism
† As first or co-first author.
Jul. 2018
Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes
Amar Abderrahmani, Loïc Yengo, Robert Caiazzo, Mickaël Canouil†, Stéphane Cauchi, […], Clemens Schafmayer, Jochen Hampe, Amélie Bonnefond, François Pattou and Philippe Froguel
Diabetes
† As first or co-first author.
Jun. 2018
Jointly Modelling Single Nucleotide Polymorphisms With Longitudinal and Time-to-Event Trait: An Application to Type 2 Diabetes and Fasting Plasma Glucose
Mickaël Canouil†, Beverley Balkau, Ronan Roussel, Philippe Froguel and Ghislain Rocheleau
Frontiers in Genetics
† As first or co-first author.
Jun. 2017
Low-dose exposure to bisphenols A, F and S of human primary adipocyte impacts coding and non-coding RNA profiles
Marie Verbanck, Mickaël Canouil†, Audrey Leloire, Véronique Dhennin, Xavier Coumoul, Loïc Yengo, Philippe Froguel and Odile Poulain-Godefroy
PLOS ONE
† As first or co-first author.
Jun. 2017
Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion
Fatou K. Ndiaye, Ana Ortalli, Mickaël Canouil†, Marlène Huyvaert, Clara Salazar-Cardozo, […], Piero Marchetti, François Pattou, Amar Abderrahmani, Philippe Froguel and Amélie Bonnefond
Molecular Metabolism
† As first or co-first author.