Main
Mickaël Canouil
Curriculum Vitæ
I am currently working as a consultant in Biostatistics in the field of genetics, i.e., proteomics, metabolomics, transcriptomics, etc. in Lille & Paris, France.
Education
Doctor of Philosophy (Ph.D.) in Biostatistics
University of Lille
Lille, France
Oct. 2014 - Sep. 2017
Master’s Degree in Biostatistics, Bioinformatics and Genomics (Specialised in Biostatistics)
University Claude Bernard Lyon 1
Lyon, France
Sep. 2009 - Jul. 2011
Bachelor’s Degree in Biology (Specialised in Biostatistics)
University Claude Bernard Lyon 1
Lyon, France
Sep. 2006 - Jul. 2009
Professional Experience
Consulting Senior Biostatistician (IT&M Stats)
L’Oréal
Lille, France
Nov. 2022 - Present
Activities: Statistical analyses of lipidomics and microbiome data
Head of Biostatistics (Institut Pasteur de Lille)
Functional (Epi)genomics and Molecular
Physiology of Diabetes and Related Diseases
Inserm U1283 / CNRS UMR 8199 - EGID
(European Genomics Institute for Diabetes)
Lille, France
Jan. 2020 - Oct. 2022
Activities: Genome-wide association studies, experimental design, -omics data analysis, methodological developments, team management
Head of Biostatistics (Institut Pasteur de Lille)
Laboratory of Integrated Genomics
and Metabolic Diseases Modeling
CNRS UMR 8199 - EGID
(European Genomics Institute for Diabetes)
Lille, France
Oct. 2017 - Dec. 2019
Activities: Genome-wide association studies, experimental design, -omics data analysis, methodological developments, team management
Head of Biostatistics (CNRS)
Laboratory of Integrated Genomics
and Metabolic Diseases Modeling
CNRS UMR 8199 - EGID
(European Genomics Institute for Diabetes)
Lille, France
Jan. 2016 - Sep. 2017
Activities: Genome-wide association studies, experimental design, -omics data analysis, methodological developments, team management
Biostatistician (CNRS)
Laboratory of Integrated Genomics
and Metabolic Diseases Modeling
CNRS UMR 8199 - EGID
(European Genomics Institute for Diabetes)
Lille, France
Sep. 2012 - Dec. 2015
Activities: Genome-wide association studies, experimental design, -omics data analysis, methodological developments
Biostatistician
French Institute of Science and Technology for
Transport, Development and Networks
(IFSTTAR)
UMRESTTE - UMR T9405
Bron, France
Nov. 2011 - Dec. 2011
Activities: Analysis of a mobility and accident study in secondary-school pupils
Biostatistician (Internship)
Hospices Civiles de Lyon
Biostatistics Unit
CNRS UMR 5558
Lyon, France
Jan. 2011 - Jun. 2011
Activities: Development of a Non-Parametric (on Time) Clustering Algorithm for Longitudinal Data
Biostatistician (Internship)
Biometry and Evolutionary Biology laboratory
(LBBE)
CNRS UMR 5558
Lyon, France
Mar. 2010 - Jun. 2010
Activities: Mathematical Modelling of Nosocomial Rotavirus Infections in Pediatric Ward
Workshop Experience (7)
Awards (1)
Funding Allocation SFD-Lilly
“Société Francophone du Diabète”
(SFD)
Bordeaux, France
Mar. 2015
Project: Detection of new genomic variants associated with fasting blood glucose and incidence of type 2 diabetes simultaneously
Oral communications (6)
My Journey To Transparency And Reproducibility (French)
Min2Rien (www.min2rien.fr)
Online (Lille, France)
Apr. 2021
Jointly Modelling SNPs With Survival & Longitudinal Trait
A Statistical Seminar Applied on Type 2 Diabetes
(Host: Pr. Paul Franks)
Lund, Sweden
Jan. 2019
Jointly Modelling SNPs With Survival & Longitudinal Trait
Thematic Day “Statistic & Genomic”
of the “Réseau Interdisciplinaire
autour de la Statistique”
(RIS) (ris.cnrs.fr)
Paris, France
Oct. 2018
Longitudinal Genetic Modelling: Revisiting Associations of SNPs Associated With Blood Fasting Glucose in Normoglycemic Individuals
Statistical Methods for Post Genomic Data
(SMPGD) (math.univ-lille1.fr/~celisse/SMPGD)
Lille, France
Feb. 2016
Poster communications (4)
“Variants Génétiques Associés à la Trajectoire de la Glycémie à Jeun et à l’Incidence du Diabète de Type 2: Une Approche par Modèle Joint” (CA-075)
Annual Congress of
“Société Francophone du Diabète”
(SFD)
Lille, France
Mar. 2017
Single Nucleotide Polymorphisms Associated With Fasting Blood Glucose Trajectory And Type 2 Diabetes Incidence: A Joint Modelling Approach
4th Symposium
European Genomic Institute for Diabetes
(EGID)
Lille, France
Nov. 2016
Single Nucleotide Polymorphisms Associated With Fasting Blood Glucose Trajectory And Type 2 Diabetes Incidence: A Joint Modelling Approach
International Genetic Epidemiology Society
(IGES)
Toronto, Canada
Oct. 2016
Application of Joint Models in Genetic Association Studies
International Genetic Epidemiology Society
(IGES)
Baltimore, United-States
Oct. 2015
R Packages (6)
insane: An Interactive Web Application for Quality Control and Analysis of Insulin Secretion from Pancreatic Beta Cells
(As author / creator)
CRAN
Nov. 2020
https://cran.r-project.org/package=insane
https://github.com/mcanouil/insane/
ggpacman: A ‘ggplot2’ and ‘gganimate’ Version of Pac-Man
(As author / creator)
CRAN
May 2020
https://cran.r-project.org/package=ggpacman
https://github.com/mcanouil/ggpacman/
ggnetwork: Geometries to Plot Networks with ‘ggplot2’
(As contributor)
CRAN
Feb. 2020
https://cran.r-project.org/package=ggnetwork
https://github.com/briatte/ggnetwork/
NACHO: NanoString Quality Control Dashboard
(As author / creator)
CRAN
Jun. 2018
https://cran.r-project.org/package=NACHO
https://github.com/mcanouil/NACHO/
clere: Simultaneous Variables Clustering and Regression
(As author)
CRAN
Feb. 2014
https://cran.r-project.org/package=clere
https://github.com/mcanouil/clere/
snpEnrichment: SNPs Enrichment Analysis
(As author / creator)
CRAN
Apr. 2013
https://cran.r-project.org/package=snpEnrichment
https://github.com/mcanouil/snpEnrichment/
Publications (7 + 36)
Epigenome-Wide Association Study Reveals Methylation Loci Associated With Offspring Gestational Diabetes Mellitus Exposure and Maternal Methylome
Mickaël Canouil†, Amna Khamis, Elina Keikkala, Sandra Hummel, Stephane Lobbens, […], Marjo-Riitta Jarvelin, Sylvain Sebert, Eero Kajantie, Philippe Froguel and Toby Andrew
N/A
Sep. 2021
† As first or co-first author.
: an R package for quality control of NanoString nCounter data
Mickaël Canouil†, Gerard A Bouland, Amélie Bonnefond, Philippe Froguel, Leen M ’t Hart and Roderick C Slieker
N/A
Feb. 2020
† As first or co-first author.
Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetes
Amna Khamis, Mickaël Canouil†, Afshan Siddiq, Hutokshi Crouch, Mario Falchi, […], Mark Ibberson, Amelie Bonnefond, Piero Marchetti, Michele Solimena and Philippe Froguel
N/A
Jun. 2019
† As first or co-first author.
Increased Hepatic PDGF-AA Signaling Mediates Liver Insulin Resistance in Obesity-Associated Type 2 Diabetes
Amar Abderrahmani, Loïc Yengo, Robert Caiazzo, Mickaël Canouil†, Stéphane Cauchi, […], Clemens Schafmayer, Jochen Hampe, Amélie Bonnefond, François Pattou and Philippe Froguel
N/A
Jul. 2018
† As first or co-first author.
Jointly Modelling Single Nucleotide Polymorphisms With Longitudinal and Time-to-Event Trait: An Application to Type 2 Diabetes and Fasting Plasma Glucose
Mickaël Canouil†, Beverley Balkau, Ronan Roussel, Philippe Froguel and Ghislain Rocheleau
N/A
Jun. 2018
† As first or co-first author.
Low-dose exposure to bisphenols A, F and S of human primary adipocyte impacts coding and non-coding RNA profiles
Marie Verbanck, Mickaël Canouil†, Audrey Leloire, Véronique Dhennin, Xavier Coumoul, Loïc Yengo, Philippe Froguel and Odile Poulain-Godefroy
N/A
Jun. 2017
† As first or co-first author.
Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion
Fatou K. Ndiaye, Ana Ortalli, Mickaël Canouil†, Marlène Huyvaert, Clara Salazar-Cardozo, […], Piero Marchetti, François Pattou, Amar Abderrahmani, Philippe Froguel and Amélie Bonnefond
N/A
Jun. 2017
† As first or co-first author.